Radius Cranberry Floss is coated with pure unsweetened cranberry essence, which is removed during the action of flossing and deposited on the gums to help break up plaque. Radius Floss is spun in natural beeswax to help sliding through tight spaces. Research has shown that the proanthocyanidins present in cranberry essence are effective in reversing and inhibiting the clumping of bacteria that cause plaque and subsequently may help in maintaining good oral hygiene. Plaque is considered the major source of pathogens that cause gingival irritation and periodontal disease.  Made in the USA.